Glycine

Thorne Glycine delivers a foundational amino acid that supports the central nervous system, healthy sleep, liver detoxification pathways, and connective tissue integrity — making it a versatile addition to a balanced, daily wellness routine.

The amino acid glycine plays a key role in maintaining a healthy central nervous system (CNS).* It is considered one of the most important inhibitory neurotransmitters in the CNS, particularly in the brainstem and spinal cord.* Studies show glycine can help improve memory retrieval in individuals with a wide variety of sleep-depriving conditions, such as jet lag and overwork.* The benefits of glycine are not just limited to the CNS. Glycine also plays a key role in phase II liver detoxification by having a direct effect on toxin elimination or by increasing the level of glutathione.* Glycine also helps modulate cytokines associated with obesity.*

Glycine is one of three amino acids needed to produce creatine, which in turn supplies energy to muscle and nerve cells.* The other two amino acids are arginine and methionine. High concentrations of glycine are found in the muscles, the skin, and other connective tissues. Approximately 30 percent of collagen is composed of glycine.

Glycine plays an important role in supporting a healthy digestive system by helping to regulate the synthesis of bile acid, which the body uses to digest fats.* Glycine also plays a role in regulating the utilization of glucose during energy production.*

Suggested Use:

Take 2 capsules one to three times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

Ways to Incorporate Thorne Glycine Into Your Routine

• Sleep and recovery support: Glycine is studied for its role in supporting memory retrieval and restfulness, particularly for those managing disrupted sleep from jet lag or demanding schedules.
• Liver and detoxification pathways: Glycine contributes to phase II liver detoxification processes and supports healthy glutathione levels as part of a comprehensive wellness approach.
• Connective tissue and muscle health: With glycine comprising approximately 30 percent of collagen, it supports the structural integrity of skin, muscle, and other connective tissues.
• Digestive wellness: Glycine helps regulate bile acid synthesis, supporting the body's natural ability to digest and process dietary fats.

Frequently Asked Questions

What is Thorne Glycine used for?

Thorne Glycine is an amino acid supplement that supports the central nervous system, liver detoxification pathways, connective tissue health, and digestive function. It is commonly included in wellness routines focused on sleep quality, recovery, and overall foundational nutrition.

Is Thorne a reputable brand for glycine supplements?

Thorne is a widely respected name in the premium supplement space, known for rigorous quality standards and science-backed formulations. Paceline curates Thorne products as part of its commitment to offering trusted, high-quality wellness brands.

How does glycine relate to collagen and creatine production?

Glycine is one of three amino acids required for the body to produce creatine, which supplies energy to muscle and nerve cells. It is also a primary structural component of collagen, accounting for roughly 30 percent of collagen's composition.