Pro-Resolving Mediators

Thorne Pro-Resolving Mediators provides EPA, DHA, and three targeted pre-resolving mediators—17-HDHA, 14-HDHA, and 18-HEPE—to support the body's natural process of returning to balance after physical stress, tissue discomfort, or intense training.

Pro-Resolving mediators (PRMs) are the end products of the body’s metabolism of EPA and DHA. Thorne’s Pro-Resolving Mediators supplement includes the precursors the body needs to create pro-resolving mediators – two pre-resolving mediators 17-HDHA and 14-HDHA from DHA and one pre-resolving mediator 18-HEPE from EPA, as well as their parents EPA and DHA, to deliver a one-two punch in support of a balanced inflammatory response.* A balanced inflammatory response helps bring the body back into homeostasis after an injury or other insult – essentially helping to “resolve” the problem.* In fact, groups of PRMs produced in the body are called resolvins and protectins – basically members of the body’s “cleanup crew.”

Benefits of Thorne’s Pro-Resolving Mediators formula:

• Provides support for healthy brain structure and cognitive function*
• Helps maintain a balanced immune/inflammatory response throughout the body*
• Provides relief from the discomfort of a tissue injury*
• Promotes clearance of cellular debris – the dead cells and byproducts of the inflammatory process*
• Supports exercise recovery*

Features

• Includes EPA and DHA in addition to three pre-resolving mediators
• Contains an omega-3 blend with the highest concentration of pre-resolving mediators on the market

Suggested Use:

Take 1 gelcap daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

The omega-3 fatty acids in Pro-Resolving Mediators are derived from fish and/or shellfish.

PREGNANCY

If pregnant, consult your health professional before using this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

How Thorne Pro-Resolving Mediators Fits Your Wellness Routine

• Post-workout recovery: Supports the body's natural resolution process after intense exercise, helping maintain comfort and readiness for the next session.
• Balanced inflammatory response: Supplies both parent omega-3s and their pre-resolving mediator derivatives to promote a healthy, balanced immune and inflammatory response throughout the body.
• Brain and cognitive support: Provides DHA-derived compounds that support healthy brain structure and cognitive function as part of a daily wellness regimen.
• Cellular cleanup support: Promotes the body's natural clearance of cellular debris—the byproducts generated during the normal inflammatory process.

Frequently Asked Questions

What makes Thorne Pro-Resolving Mediators different from a standard fish oil supplement?

Unlike standard fish oil, this formula includes not only EPA and DHA but also three specific pre-resolving mediators—17-HDHA, 14-HDHA, and 18-HEPE—which are the precursors the body uses to create pro-resolving mediators. This delivers a more targeted approach to supporting a balanced inflammatory response.

Who is Thorne Pro-Resolving Mediators best suited for?

It is well-suited for active individuals, those managing the demands of regular training, or anyone looking to support a balanced inflammatory response and exercise recovery as part of a broader wellness routine.

Is Thorne Pro-Resolving Mediators third-party tested for quality?

Thorne is a brand known for rigorous quality standards and manufacturing integrity. For specific testing and certification details, refer to the product label or Thorne's official documentation.