Riboflavin 5'-Phosphate

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Why We Chose This

This bioactive form of riboflavin bypasses conversion issues, delivering B2 directly where your body needs it for energy metabolism, red blood cell production, and hormonal balance. If digestive stress or medications compromise your nutrient absorption, R5P ensures you're getting the activated support your system requires to perform at its best.

Thorne Riboflavin 5'-Phosphate provides vitamin B2 in its active, bioavailable form—riboflavin 5'-phosphate (R5P)—so the body can utilize it directly without conversion. Formulated without yeast, it supports fat and glucose metabolism, red blood cell synthesis, and the activation of other B vitamins as part of a consistent wellness routine.

Riboflavin, also known as vitamin B2, is necessary for the body to be able to activate vitamin B6.* Riboflavin is also necessary for the body's conversion of tryptophan to niacin, and the conversion of folate to folate's various active forms.* In addition, riboflavin plays a crucial role in the metabolism of fats and glucose, the synthesis of red blood cells, healthy methylation, and the production and regulation of certain hormones.*

To be utilized by the body, however, riboflavin must first be converted to its active form – riboflavin 5'-phospate (R5P). A compromised digestive system, however, can adversely affect the body's ability to convert riboflavin to R5P.* And certain prescription medications can also compromise the absorption of riboflavin, putting it in a state of deficiency. Thorne's Riboflavin 5'-Phosphate, which is not derived from yeast, provides supplementation with a bioactive, tissue ready form of riboflavin that can be optimally utilized in the body.*

Suggested Use:

Take 1 capsule one to three times daily or as recommended by your health professional.

Warnings:

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY
If pregnant, consult your health professional before using this product.

INTERACTIONS
There are no known adverse interactions or contraindications at publication date.

Who Riboflavin 5'-Phosphate Is Designed For

Those seeking active B2: Individuals who want a bioavailable, tissue-ready form of riboflavin rather than standard riboflavin that requires conversion in the body.
People supporting B-vitamin balance: Riboflavin 5'-phosphate plays a role in activating vitamin B6 and converting folate to its active forms, making it a foundational part of a comprehensive B-vitamin routine.
Anyone focused on energy metabolism: R5P supports the metabolism of fats and glucose, which is relevant for those with active lifestyles or demanding daily schedules.
Yeast-sensitive individuals: Thorne's formulation is not derived from yeast, making it a considered option for those mindful of common allergen sources in supplements.

Frequently Asked Questions

What makes riboflavin 5'-phosphate different from regular riboflavin?

Riboflavin 5'-phosphate (R5P) is the active, coenzyme form of vitamin B2 that the body can use directly, without requiring conversion. This can be particularly relevant for those with digestive challenges that may affect the conversion process.

Is Thorne Riboflavin 5'-Phosphate yeast-free?

Yes, Thorne's Riboflavin 5'-Phosphate is not derived from yeast, which distinguishes it from some other riboflavin supplements on the market.

How does riboflavin 5'-phosphate support other B vitamins?

Riboflavin is necessary for the body to activate vitamin B6 and to convert folate into its various active forms, as well as to support the conversion of tryptophan to niacin. This makes it a key cofactor in a broader B-vitamin routine.